Description

tert-Butyl 4-Amino-3-Methyl-1-Piperidinecarboxylate is a high-purity, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel compounds and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and pesticides, leveraging its functionalized piperidine core.
• Fine Chemical Production: Serves as a versatile precursor in the synthesis of complex specialty chemicals and ligands for catalysis.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Peptidomimetic Chemistry: The protected amino group makes it suitable for constructing peptide analogs and bioisosteres.

Basic Information

Product Name	tert-Butyl 4-Amino-3-Methyl-1-Piperidinecarboxylate
CAS No.	900642-17-3
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	1-Boc-4-Amino-3-methylpiperidine; 4-Amino-3-methylpiperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-amino-3-methylpiperidine-1-carboxylate; 3-Methyl-4-aminopiperidine-1-carboxylic acid tert-butyl ester; 1-N-Boc-4-Amino-3-methylpiperidine; 4-Amino-3-methyl-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; Boc-4-Amino-3-methylpiperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Amino-3-Methyl-1-Piperidinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.