Description

Pyrrolo[2,1-B]Thiazole-5-Carbonyl Chloride, 2,3-Dihydro- (9Ci) is a specialized heterocyclic building block featuring a reactive acid chloride functional group. This compound is of significant value in organic synthesis, particularly in the pharmaceutical and agrochemical sectors, where it serves as a key intermediate for constructing complex molecular architectures. It is primarily sought after by research chemists and process development scientists working on novel active ingredients, including potential kinase inhibitors and other biologically relevant heterocycles. The CAS number for this compound is 99955-73-4.

Application

This high-purity chemical intermediate is designed for advanced synthetic applications, enabling the creation of novel compounds with potential biological activity.

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the discovery and development of new active ingredients for crop protection products.
• Chemical Biology & Probe Development: Serves as a scaffold for creating molecular probes to study biological pathways and protein functions.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or advanced polymers with specific heterocyclic motifs.
• Custom Synthesis & Contract Manufacturing: An essential reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Item	Details
Product Name	Pyrrolo[2,1-B]Thiazole-5-Carbonyl Chloride, 2,3-Dihydro- (9Ci)
CAS No.	99955-73-4
Molecular Formula	C8H6ClNOS
Molecular Weight	199.66 g/mol
Synonyms	2,3-Dihydropyrrolo[2,1-b]thiazole-5-carbonyl chloride; 5-Thiazolecarbonyl chloride, 2,3-dihydro-2-(1H-pyrrol-1-yl)-; Pyrrolo[2,1-b]thiazole-5-carbonyl chloride, 2,3-dihydro-; 99955-73-4; 2,3-Dihydro-1H-pyrrolo[2,1-b][1,3]thiazole-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of Pyrrolo[2,1-B]Thiazole-5-Carbonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.