Description

Isopropyl Chloroformate is a versatile and highly reactive organic compound primarily used as a key reagent in chemical synthesis. Its value lies in its role as an efficient chloroformylating and coupling agent, enabling the formation of carbonates, carbamates, and other functional groups under controlled conditions. This product is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and specialty chemical industries, where it facilitates the production of active ingredients and advanced intermediates.

Application

• Pharmaceutical intermediate synthesis, particularly for the production of carbamate-based drugs and prodrugs.
• Agrochemical manufacturing, serving as a building block for herbicides, fungicides, and insecticides.
• Polymer chemistry as a monomer or modifying agent for specialty polycarbonates and polyurethanes.
• Peptide synthesis as a coupling reagent for protecting amino groups.
• Production of isopropyl carbonates and other ester derivatives.
• Organic synthesis reagent for introducing the isopropoxycarbonyl protecting group.
• Chemical research and development for exploring novel synthetic pathways.

Basic Information

Product Name	Isopropyl Chloroformate
CAS No.	108-23-6
Molecular Formula	C4H7ClO2
Molecular Weight	122.55 g/mol
Synonyms	Isopropyl chlorocarbonate; Chloroformic acid isopropyl ester; Isopropoxycarbonyl chloride; IPCF; Carbonochloridic acid, 1-methylethyl ester; Propan-2-yl carbonochloridate; Isopropylcarbonyl chloride
EINECS	203-563-6

Quality Control

Our Isopropyl Chloroformate is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including gas chromatography (GC) for assay and impurity profiling, to meet exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and safety parameters is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases, amines, and alcohols. Due to its highly volatile and moisture-sensitive nature, it is recommended to store under an inert atmosphere (e.g., nitrogen) and keep containers tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0 %
Water Content (Karl Fischer)	≤ 0.1 %
Density at 20°C	1.07 - 1.09 g/cm³
Refractive Index (n20D)	1.400 - 1.404

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.