Description

2-Chlorobutyryl Chloride is a versatile and highly reactive acid chloride intermediate essential for introducing the 2-chlorobutyryl moiety into target molecules. Its primary value lies in enabling efficient synthesis and functionalization in advanced organic chemistry, particularly for building complex pharmacologically active structures. This compound is a critical raw material for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of novel therapeutic agents.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, where the chlorobutyryl group is integral to biological activity.
• Peptide Chemistry: Employed as an acylating agent for the modification of amino acids and peptides.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialty polymers and resins.
• Organic Synthesis Reagent: A fundamental reagent for Friedel-Crafts acylation and other nucleophilic substitution reactions in fine chemical manufacturing.
• Dye and Pigment Production: Acts as an intermediate in the synthesis of complex organic dyes and colorants.

Basic Information

Product Name	2-Chlorobutyryl Chloride
CAS No.	7623-11-2
Molecular Formula	C4H6Cl2O
Molecular Weight	141.00 g/mol
Synonyms	Butanoyl chloride, 2-chloro-; 2-Chlorobutanoyl chloride; α-Chlorobutyryl chloride; NSC 8805; Butyryl chloride, 2-chloro-; 2-Chloro-1-oxobutyl chloride
EINECS	231-558-8

Quality Control

Our 2-Chlorobutyryl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, alcohols, and amines. Due to its hygroscopic and strong acid/organic solvent nature, containers must be kept tightly sealed under a dry inert atmosphere to prevent hydrolysis and degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.