Description

Palmitoyl Chloride CAS NO 112-67-4 is a key fatty acid chloride derivative, serving as a versatile and reactive acylating agent in organic synthesis. Its primary value lies in its ability to efficiently introduce the palmitoyl group, a common C16 fatty acid chain, into target molecules, enabling the production of esters, amides, and ketones. This compound is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, cosmetic, and specialty chemical industries, where it is used to synthesize surfactants, lubricant additives, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediates: Critical for the synthesis of prodrugs and active pharmaceutical ingredients (APIs) requiring lipophilic modification for enhanced bioavailability.
• Surfactant & Emulsifier Production: Used to manufacture palmitate esters (e.g., isopropyl palmitate) and amides, which are key components in personal care products, cosmetics, and industrial cleaners.
• Agrochemical Synthesis: Acts as a building block for creating pesticides, herbicides, and plant growth regulators with specific activity profiles.
• Polymer & Resin Modification: Employed as a coupling agent or modifier to alter the surface properties and performance of polymers and coatings.
• Lubricant & Fuel Additives: Key intermediate in producing additives that improve viscosity, reduce friction, and enhance stability in lubricants and fuels.
• Bioconjugation & Biochemical Research: Utilized in lipid biochemistry for protein lipidation studies and the synthesis of fluorescent probes or other labeled compounds.
• Fragrance & Flavor Chemistry: Serves as a precursor for synthesizing specific aroma chemicals and flavor esters.

Basic Information

Product Name	Palmitoyl Chloride
CAS No.	112-67-4
Molecular Formula	C₁₆H₃₁ClO
Molecular Weight	274.87 g/mol
Synonyms	Hexadecanoyl Chloride; Cetyl Chloride; Palmitic Acid Chloride; n-Hexadecanoyl Chloride; Palmityl Chloride; 1-Pentanecarbonyl Chloride, 10-butyl-; Chloride de palmitoyle (French); Palmitoylchlorid (German)
EINECS	203-997-2

Quality Control

Our Palmitoyl Chloride is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including assay by titration and impurity profiling, to ensure it meets high-purity standards suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and specific test results is provided with each shipment and is available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties as a strong acid/organic solvent, hygroscopic (moisture-sensitive), and highly volatile nature, it must be stored in a cool, dry, and well-ventilated area, ideally at 2-8°C (refrigerated) or as specified on the label. The container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (Titration)	≥ 97.0%
Acid Value	≤ 5.0 mg KOH/g
Water Content (KF)	≤ 0.1%
Free Chloride	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.