Description

[1S-(1Alpha,2Alpha,4Alpha,5Beta)]-2-(5-Vinyl-1-Azabicyclo[2.2.2]Oct-2-Yl)-1H-Indole-3-Ethanol Monohydrochloride is a high-purity, complex organic compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chiral intermediate or reference standard in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies focused on developing new therapeutic agents, particularly in the fields of neurology and oncology.

Application

• Pharmaceutical Intermediate: A key chiral building block in the multi-step synthesis of complex drug candidates.
• Reference Standard: Used for analytical method development, validation, and quality control in API manufacturing.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Process Chemistry Development: Serves as a benchmark for scaling up synthetic routes from laboratory to pilot plant scale.
• Academic Research: Utilized in university and institutional labs for studying alkaloid chemistry and novel heterocyclic compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing outsourced drug discovery and development services.

Basic Information

Product Name	[1S-(1Alpha,2Alpha,4Alpha,5Beta)]-2-(5-Vinyl-1-Azabicyclo[2.2.2]Oct-2-Yl)-1H-Indole-3-Ethanol Monohydrochloride
CAS No.	99604-17-8
Molecular Formula	C19H25ClN2O
Molecular Weight	332.87 g/mol
Synonyms	(1S,2S,4S,5R)-2-(5-Vinylquinuclidin-2-yl)-1H-indole-3-ethanol hydrochloride; 2-((1S,2S,4S,5R)-5-Vinyl-2-quinuclidinyl)-1H-indole-3-ethanol hydrochloride; 3-(2-Hydroxyethyl)-2-((1S,2S,4S,5R)-5-vinyl-2-quinuclidinyl)indole hydrochloride; Vinylquinuclidinylindoleethanol hydrochloride; 99604-17-8; Contact for additional IUPAC names and research codes.
EINECS	Contact for details

Quality Control

Every batch of [1S-(1Alpha,2Alpha,4Alpha,5Beta)]-2-(5-Vinyl-1-Azabicyclo[2.2.2]Oct-2-Yl)-1H-Indole-3-Ethanol Monohydrochloride is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.