Description

1-(Phenylsulfonyl)-1H-Indole-3-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound matters for its role as a key building block in constructing complex heterocyclic frameworks, enabling the development of novel active molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of potential drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of indole-based drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides and fungicides that leverage the indole scaffold for biological activity.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic materials.
• Academic & R&D: A valuable reagent in university and contract research laboratories for exploring new chemical reactions and synthesizing complex heterocycles.
• Peptide Mimetics: Employed in the design and synthesis of peptidomimetics and other bioactive molecules that incorporate modified indole structures.

Basic Information

Product Name	1-(Phenylsulfonyl)-1H-Indole-3-Carbonyl Chloride
CAS No.	99532-51-1
Molecular Formula	C15H10ClNO3S
Molecular Weight	319.76 g/mol
Synonyms	1-(Phenylsulfonyl)-1H-indole-3-carbonyl chloride; 1H-Indole-3-carbonyl chloride, 1-(phenylsulfonyl)-; 1-Benzenesulfonylindole-3-carbonyl chloride; 3-Chlorocarbonyl-1-(phenylsulfonyl)indole; 1-(Phenylsulfonyl)indole-3-carbonyl chloride; 99532-51-1; 1-Phenylsulfonylindole-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)-1H-Indole-3-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical R&D and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.