Description

Cucurbitacin F-25-Acetate is a specific, acetylated derivative of the cucurbitacin family of highly oxygenated tetracyclic triterpenoids. This compound is valued for its potent bioactivity, serving as a critical reference standard and a key intermediate in pharmaceutical research and development. It is primarily sought by researchers and manufacturers in the life sciences sector for applications in oncology, anti-inflammatory studies, and metabolic pathway investigations.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the qualitative and quantitative analysis of cucurbitacin derivatives in drug discovery and quality control laboratories.
• Oncology Research: Investigated for its cytotoxic properties and potential mechanisms of action in various cancer cell line studies.
• Anti-inflammatory Agent Development: Serves as a lead compound or intermediate in the synthesis of novel anti-inflammatory therapeutics.
• Biochemical Pathway Analysis: Employed as a molecular probe to study signaling pathways, such as JAK/STAT, due to its specific inhibitory effects.
• Natural Product Synthesis: Acts as a key chiral building block or intermediate in the semi-synthesis of complex natural products and their analogs.
• Academic & Institutional Research: Utilized in universities and research institutes for pharmacological, phytochemical, and toxicological studies.

Basic Information

Product Name	Cucurbitacin F-25-Acetate
CAS No.	99530-82-2
Molecular Formula	C₃₂H₄₆O₈
Molecular Weight	558.71 g/mol
Synonyms	Cucurbitacin F 25-acetate; 25-O-Acetyl-23,24-dihydrocucurbitacin F; 2β,16α,20(R),25-Tetrahydroxy-3,11,22-trioxo-9-methyl-19-norlanosta-5,23-dien-25-yl acetate; 23,24-Dihydrocucurbitacin F 25-acetate; (20R)-2β,16α,20,25-Tetrahydroxy-9-methyl-19-nor-9β-lanosta-5,23-diene-3,11,22-trione 25-acetate
EINECS	Contact for details

Quality Control

Our Cucurbitacin F-25-Acetate is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the product at 2-8°C. The container should be kept tightly sealed in a dry, well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.