Description

(E)-Aztreonam CAS NO 99341-02-3 is a synthetic monobactam antibiotic belonging to the β-lactam class, specifically designed to be highly resistant to β-lactamase enzymes. This property makes it a critical agent for targeting serious Gram-negative bacterial infections where other antibiotics may fail. It is an essential active pharmaceutical ingredient (API) for the formulation of injectable and inhalation medications, primarily serving the pharmaceutical research, development, and manufacturing sectors.

Application

• Pharmaceutical API: Primary use as the active ingredient in sterile injectable formulations for systemic treatment of severe Gram-negative infections.
• Inhalation Therapy: Key component in drug formulations for managing chronic pulmonary infections in conditions like cystic fibrosis.
• Antibiotic Research: Serves as a reference standard and building block in microbiological research and the development of new antibacterial agents.
• Veterinary Medicine: Used in the development of treatments for bacterial infections in animals.
• Clinical Laboratory Standards: Employed as a control substance in antimicrobial susceptibility testing (AST).

Basic Information

Item	Details
Product Name	(E)-Aztreonam
CAS No.	99341-02-3
Molecular Formula	C13H17N5O8S2
Molecular Weight	435.43 g/mol
Synonyms	Aztreonam; Azactam; SQ 26,776; (Z)-2-[[[(2-Amino-4-thiazolyl)[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]carbamoyl]methylene]amino]oxy-2-methylpropionic acid; Monobactam antibiotic; 3-(((Z)-(1-(2-Amino-4-thiazolyl)-2-(((2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino)-2-oxoethylidene)amino)oxy)-2-methylpropanoic acid
EINECS	Contact for details

Quality Control

Our (E)-Aztreonam is manufactured and tested under strict quality management systems. Each batch is analyzed to meet high-purity standards suitable for pharmaceutical applications, with testing typically including identification, assay, impurity profile, and residual solvents. A comprehensive Certificate of Analysis (COA) documenting compliance with relevant specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.