Description

1-Docosahexaenoin-2-Oleoyl 3-Phosphocholine is a high-purity, structured phospholipid designed for advanced research and formulation. This compound is critical for developing sophisticated lipid-based delivery systems due to its unique combination of DHA and oleic acid moieties. It is primarily sought by researchers and manufacturers in the pharmaceutical, nutraceutical, and advanced cosmetics industries for creating targeted liposomes, lipid nanoparticles, and other complex lipid assemblies.

Application

• Lipid Nanoparticle (LNP) Formulation: A key synthetic phospholipid component for constructing stable, targeted LNPs for mRNA and siRNA delivery.
• Advanced Liposome Development: Used to engineer specialized liposomal carriers with enhanced membrane fluidity and targeting capabilities for drug delivery.
• Biomimetic Membrane Research: Serves as a critical building block in synthetic biology for creating model cell membranes that mimic specific phospholipid compositions.
• Nutraceutical Encapsulation: Employed in the encapsulation of sensitive bioactive compounds, leveraging its structural properties for improved bioavailability and stability.
• Cosmetic Actives Delivery: Incorporated into high-end cosmetic formulations to enhance the skin penetration and efficacy of active ingredients.
• Biochemical & Diagnostic Reagents: Used as a standard or a key reagent in analytical methods and diagnostic kit development related to lipid metabolism.

Basic Information

Product Name	1-Docosahexaenoin-2-Oleoyl 3-Phosphocholine
CAS No.	99265-02-8
Molecular Formula	C52H94NO8P
Molecular Weight	892.28 g/mol
Synonyms	DHA-OA PC; 1-Docosahexaenoyl-2-oleoyl-sn-glycero-3-phosphocholine; (22:6-18:1) PC; 1-DHA-2-OA-PC; 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine; O-DHA-PC; Phosphatidylcholine (22:6/18:1); Structured Phospholipid DHA/Oleic Acid
EINECS	Contact for details

Quality Control

Our 1-Docosahexaenoin-2-Oleoyl 3-Phosphocholine is manufactured under strict quality systems. Each batch is characterized and tested to ensure high purity and structural integrity, with specifications suitable for research and GMP-grade applications. Comprehensive analytical data, including NMR and Mass Spectrometry confirmation, is provided. Certificates of Analysis (COA) are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. Allow the sealed container to reach room temperature before opening to minimize moisture absorption. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white waxy solid or oil
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Assay (HPLC)	≥ 95%
Solvent Content (Residual)	≤ 1.0%
Water Content (KF)	≤ 1.0%
Peroxide Value	≤ 5.0 meq/kg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.