Description

2-(2-(4-((2,3,4-Trimethoxyphenyl)Methyl)-1-Piperazinyl)Ethoxy)Ethanol Dihydrochloride is a high-purity, complex organic salt of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate or active pharmaceutical ingredient (API) precursor, valued for its precise chemical structure and functionality. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly within the realms of central nervous system (CNS) and cardiovascular research.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of potential drug candidates, especially those targeting neurological pathways.
• Biochemical Research: Used as a reference standard or reagent in pharmacological studies to investigate receptor binding and enzyme inhibition.
• API Development: Serves as a precursor in the development and scale-up of new Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Employed in university and institutional labs for medicinal chemistry projects and structure-activity relationship (SAR) studies.
• Process Chemistry: Utilized in route scouting and optimization for the efficient commercial production of complex molecules.

Basic Information

Product Name	2-(2-(4-((2,3,4-Trimethoxyphenyl)Methyl)-1-Piperazinyl)Ethoxy)Ethanol Dihydrochloride
CAS No.	99153-49-8
Molecular Formula	C18H30N2O5 • 2HCl
Molecular Weight	423.36 g/mol (free base: 354.44 g/mol)
Synonyms	1-[2-[2-Hydroxyethoxy]ethyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine dihydrochloride; 2-[2-[4-[(2,3,4-Trimethoxyphenyl)methyl]piperazin-1-yl]ethoxy]ethanol dihydrochloride; Trimethoxyphenylmethylpiperazinyl ethoxyethanol dihydrochloride; NSC 339539; GYKI-12,743 dihydrochloride; GYKI 12743 dihydrochloride; 1-(2-(2-Hydroxyethoxy)ethyl)-4-((2,3,4-trimethoxybenzyl))piperazine dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-(2-(4-((2,3,4-Trimethoxyphenyl)Methyl)-1-Piperazinyl)Ethoxy)Ethanol Dihydrochloride is manufactured under stringent quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.