Description

2'-Deoxycardiolipin (Diphosphatidyl-1,3-Propanediol) is a specialized phospholipid analog, a key structural component and research tool in membrane biochemistry. This compound is valued for its role in studying mitochondrial membrane dynamics, bioenergetics, and apoptosis. It is primarily utilized by researchers and manufacturers in the life sciences sector, particularly in pharmaceutical R&D, lipidomics, and the development of advanced drug delivery systems.

Application

• Biochemical Research: A critical reagent for studying mitochondrial structure, function, and the role of cardiolipin analogs in cellular processes like apoptosis and autophagy.
• Pharmaceutical Development: Used in the research and formulation of novel therapeutics targeting mitochondrial dysfunction, metabolic diseases, and neurodegenerative disorders.
• Lipidomics & Analytical Standards: Serves as a high-purity reference standard for mass spectrometry and chromatographic analysis in lipid profiling studies.
• Membrane Biophysics: Employed to create model membrane systems (e.g., liposomes, bilayers) for investigating protein-lipid interactions and membrane permeability.
• Drug Delivery Systems: Investigated as a component in the design of targeted liposomal and nanoparticle delivery vehicles for enhanced cellular uptake.
• Enzyme Studies: Used as a substrate or inhibitor in enzymatic assays to study phospholipase activity and lipid metabolism pathways.

Basic Information

Product Name	2'-Deoxycardiolipin (Diphosphatidyl-1,3-Propanediol)
CAS No.	99018-93-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Diphosphatidyl-1,3-propanediol; 1,3-Bis(phosphatidyl)propane; Deoxycardiolipin; Cardiolipin analog; Bis(diacylglyceryl)propane-1,3-diphosphate; Synthetic cardiolipin derivative; 2'-Deoxy-CL; Diphosphatidylpropanediol
EINECS	Contact for details

Quality Control

Our 2'-Deoxycardiolipin is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles for manufacturing and can support regulatory documentation requirements for preclinical research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This material is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.