Description

Dimethyl (2S,4R)-Piperidine-2,4-Dicarboxylate is a high-purity, stereochemically defined chiral building block and synthetic intermediate. This compound is valued for its rigid, functionalized piperidine scaffold, which is a privileged structure in medicinal chemistry and asymmetric synthesis. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex bioactive molecules, including potential drug candidates and chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of central nervous system (CNS) active drugs, enzyme inhibitors, and receptor modulators.
• Asymmetric Synthesis: Serves as a precursor for chiral auxiliaries, catalysts, and ligands used in stereoselective transformations.
• Agrochemical Research: Used in the synthesis of novel, stereospecific pesticides and herbicides.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	Dimethyl (2S,4R)-Piperidine-2,4-Dicarboxylate
CAS No.	98935-65-0
Molecular Formula	C9H15NO4
Molecular Weight	201.22 g/mol
Synonyms	Dimethyl (2S,4R)-2,4-Piperidinedicarboxylate; (2S,4R)-Dimethyl Piperidine-2,4-Dicarboxylate; (2S,4R)-2,4-Piperidinedicarboxylic Acid Dimethyl Ester; L-threo-2,4-Piperidinedicarboxylic Acid Dimethyl Ester; (2S,4R)-1,2,3,6-Tetrahydropyridine-2,4-dicarboxylic Acid Dimethyl Ester; Chiral Piperidine Diester; CAS 98935-65-0
EINECS	Contact for details

Quality Control

Our Dimethyl (2S,4R)-Piperidine-2,4-Dicarboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Production adheres to cGMP guidelines where applicable. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. We support regulatory filings with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.