Description

[17R,13α,(-)]-7α,17-Dihydroxy-2α,11α-Dimethoxy-4β,8-Dimethyl-1-Oxo-24-Nor-16,17-Seco-5α-Chola-14,20(22)-Diene-16,23-Dioic Acid 16,7:23,17-Dilactone is a complex, high-purity steroidal lactone derivative of significant interest in advanced organic synthesis. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for the development of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of steroid-based therapeutics and the exploration of new chemical entities.

Application

• Advanced Pharmaceutical Intermediate (API): A key chiral precursor in the multi-step synthesis of complex steroid-based drug candidates.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and the design of new therapeutic agents targeting hormone receptors or specific enzymes.
• Process Chemistry Development: Serves as a critical intermediate for optimizing synthetic routes and scaling up production of target molecules in a GMP environment.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis using HPLC, LC-MS, or NMR.
• Organic Synthesis Building Block: Its unique fused-ring lactone structure makes it valuable for constructing complex natural product analogs and other specialized organic compounds.

Basic Information

Product Name	[17R,13α,(-)]-7α,17-Dihydroxy-2α,11α-Dimethoxy-4β,8-Dimethyl-1-Oxo-24-Nor-16,17-Seco-5α-Chola-14,20(22)-Diene-16,23-Dioic Acid 16,7:23,17-Dilactone
CAS No.	98874-67-0
Molecular Formula	C26H34O8
Molecular Weight	474.55 g/mol
Synonyms	24-Nor-16,17-seco-5α-chola-14,20(22)-diene-16,23-dioic acid, 7α,17-dihydroxy-2α,11α-dimethoxy-4β,8-dimethyl-1-oxo-, 16,7:23,17-dilactone, (17R,13α)-; 16,17-Secocholanic Acid Dilactone Derivative; Steroidal Dilactone Intermediate; (17R,13α)-7α,17-Dihydroxy-2α,11α-dimethoxy-4β,8-dimethyl-1-oxo-24-nor-16,17-seco-5α-chola-14,20(22)-diene-16,23-dioic acid 16,7:23,17-dilactone
EINECS	Contact for details

Quality Control

Our [17R,13α,(-)]-7α,17-Dihydroxy-2α,11α-Dimethoxy-4β,8-Dimethyl-1-Oxo-24-Nor-16,17-Seco-5α-Chola-14,20(22)-Diene-16,23-Dioic Acid 16,7:23,17-Dilactone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.