Description

[1As,6Ar,9Ar,10As]-1A-[(Acetyloxy)Methyl]-2,3,6,6A,9,9A,10,10A-Octahydro-5,9-Bis(Methylene)Oxireno[4,5]Cyclodeca[1,2-B]Furan-4,8(1Ah,5H)-Dione is a complex, high-purity sesquiterpene lactone derivative with a unique oxireno-fused cyclodecane structure. This compound is valued as a critical advanced synthetic intermediate and a scaffold for pharmaceutical research due to its intricate molecular architecture and reactive functional groups. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting anti-inflammatory or anti-cancer pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Acts as a precursor for creating new plant protection agents with potential insecticidal or fungicidal activity.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to construct complex natural product analogs or specialty chemicals.
• Biochemical Probe Development: Utilized in research to develop molecular probes for studying biological pathways and enzyme interactions.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in organic chemistry and chemical biology.

Basic Information

Product Name	[1As,6Ar,9Ar,10As]-1A-[(Acetyloxy)Methyl]-2,3,6,6A,9,9A,10,10A-Octahydro-5,9-Bis(Methylene)Oxireno[4,5]Cyclodeca[1,2-B]Furan-4,8(1Ah,5H)-Dione
CAS No.	98659-28-0
Molecular Formula	C18H20O6
Molecular Weight	332.35 g/mol
Synonyms	1a-(Acetoxymethyl)-1a,2,3,6,6a,9,9a,10,10a-decahydro-5,9-bis(methylene)oxireno[4,5]cyclodeca[1,2-b]furan-4,8-dione; Parthenolide derivative; Oxireno[4,5]cyclodeca[1,2-b]furan-4,8-dione, 1a-[(acetyloxy)methyl]decahydro-5,9-bis(methylene)-, [1aS-(1aα,2α,6aβ,9aα,10aβ)]-; Sesquiterpene lactone acetate; (1aS,2S,6aR,9aS,10aR)-1a-[(Acetyloxy)methyl]decahydro-5,9-bis(methylene)oxireno[4,5]cyclodeca[1,2-b]furan-4,8-dione
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.