Description

Bis-Aminooxy-Peg2 is a specialized heterobifunctional polyethylene glycol (PEG) crosslinker featuring two aminooxy groups. This compound is highly valued for its role in bioconjugation and click chemistry, enabling the stable and site-specific coupling of biomolecules under mild, aqueous conditions. It is an essential reagent for researchers and manufacturers in the fields of biopharmaceutical development, advanced material science, and diagnostic assay production.

Application

• Bioconjugation Reagent: For the site-specific coupling of peptides, proteins, and oligonucleotides via oxime ligation.
• PEGylation Linker: Used to create PEGylated therapeutics to improve pharmacokinetic properties such as solubility and circulation half-life.
• Hydrogel Formation: Acts as a crosslinker for creating biocompatible hydrogels for drug delivery and tissue engineering scaffolds.
• Surface Functionalization: Modifies nanoparticles, biosensors, and microarray surfaces with aminooxy-reactive groups for biomolecule immobilization.
• Antibody-Drug Conjugate (ADC) Development: Facilitates the stable linkage between cytotoxic payloads and monoclonal antibodies.
• Diagnostic Probe Synthesis: Used in the preparation of labeled probes and contrast agents for imaging and detection.

Basic Information

Product Name	Bis-Aminooxy-Peg2
CAS No.	98627-71-5
Molecular Formula	C₁₂H₂₆N₂O₆
Molecular Weight	294.35 g/mol
Synonyms	1,11-Bis(aminooxy)-3,6,9-trioxaundecane; 2,2'-(Ethylenedioxy)bis(ethylamine) N-oxide derivative; PEG2 bis(aminooxy)ethane; Aminooxy-PEG2-aminooxy; O,O'-Bis(2-aminooxyethyl)triethylene glycol; Heterobifunctional PEG crosslinker, aminooxy-aminooxy
EINECS	Contact for details

Quality Control

Our Bis-Aminooxy-Peg2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and bioproduction. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, containers should be sealed under an inert atmosphere (e.g., nitrogen or argon) after opening and allowed to equilibrate to room temperature before use to prevent condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Functional Group Assay	≥ 90% (by titration)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.