Description

1-Piperazinepropanethiol,4-Methyl-(9Ci) CAS NO 98455-00-6 is a specialized heterocyclic compound featuring a piperazine core functionalized with a propanethiol group. This structure makes it a valuable building block and intermediate in advanced organic synthesis, particularly for introducing sulfur-containing moieties. It is primarily utilized by research institutions and industrial R&D departments engaged in the development of novel chemical entities. Its applications span the creation of potential pharmaceutical candidates, agrochemicals, and functional materials where precise molecular modification is required.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for molecules requiring a functionalized piperazine scaffold.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides where the thiol and amine functionalities can impart specific biological activity.
• Ligand and Catalyst Preparation: Acts as a precursor for chelating ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and metal complex formation.
• Polymer Modification: Employed to introduce amine and thiol groups into polymer chains, modifying properties like adhesion, cross-linking potential, and surface functionality.
• Bioconjugation Chemistry: The thiol group is reactive towards maleimides and other electrophiles, making it useful for protein labeling, antibody-drug conjugate (ADC) research, and probe synthesis.
• Material Science Research: Investigated for use in creating functionalized surfaces, nanomaterials, and as a component in specialty coatings.

Basic Information

Item	Detail
Product Name	1-Piperazinepropanethiol,4-Methyl-(9Ci)
CAS No.	98455-00-6
Molecular Formula	C8H18N2S
Molecular Weight	174.31 g/mol
Synonyms	4-Methyl-1-piperazinepropanethiol; 1-Piperazinepropanethiol, 4-methyl-; 3-(4-Methylpiperazin-1-yl)propane-1-thiol; 4-Methylpiperazine-1-propanethiol; 1-(3-Mercaptopropyl)-4-methylpiperazine; 4-Methyl-1-(3-sulfanylpropyl)piperazine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Each batch of 1-Piperazinepropanethiol,4-Methyl-(9Ci) is analyzed to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing specifications such as assay (by HPLC), identity confirmation (by IR/NMR), and impurity profiles. Our quality system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Due to its sensitivity to oxidation, the container should be kept sealed and only opened under controlled conditions. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.