Description

2,3,4,5-Tetrahydro-2,8-Dimethyl-5-[2-(6-Methyl-3-Pyridyl)Ethyl]-1H-Pyrido[4,3-B]Indole Dihydrochloride is a high-purity, complex heterocyclic compound supplied as a dihydrochloride salt. This product is critical for advanced research and development in medicinal chemistry, particularly in the synthesis and study of novel pharmacologically active agents. It serves as a key intermediate or reference standard for pharmaceutical companies and research institutions focused on central nervous system (CNS) and neurological disorder targets.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in API manufacturing.
• Biochemical Research: Employed in vitro and in vivo studies to investigate specific receptor interactions and biological mechanisms.
• Contract Research & Development (CRO): Supplied to CROs and academic labs for proprietary client projects and exploratory research.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing production processes for potential active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2,3,4,5-Tetrahydro-2,8-Dimethyl-5-[2-(6-Methyl-3-Pyridyl)Ethyl]-1H-Pyrido[4,3-B]Indole Dihydrochloride
CAS No.	97657-92-6
Molecular Formula	C21H27N3 • 2HCl
Molecular Weight	402.38 g/mol (free base: 321.46 g/mol)
Synonyms	5-[2-(6-Methylpyridin-3-yl)ethyl]-2,8-dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride; 2,3,4,5-Tetrahydro-2,8-dimethyl-5-(2-(6-methyl-3-pyridinyl)ethyl)-1H-pyrido[4,3-b]indole dihydrochloride; 97657-92-6; 1H-Pyrido[4,3-b]indole, 2,3,4,5-tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-, dihydrochloride; Tetrahydro Dimethyl Pyridyl Ethyl Pyridoindole Dihydrochloride
EINECS	Contact for details

Quality Control

Our 2,3,4,5-Tetrahydro-2,8-Dimethyl-5-[2-(6-Methyl-3-Pyridyl)Ethyl]-1H-Pyrido[4,3-B]Indole Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research and development. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and analytical methods (e.g., HPLC, NMR) are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.