Description

Lipoxin B4 Methyl Ester is a stable synthetic analog of the specialized pro-resolving mediator (SPM) Lipoxin B4. This compound is of significant interest for its role in modulating inflammatory pathways and promoting the resolution of inflammation without immunosuppression. It serves as a critical research tool for scientists in pharmacology, immunology, and biochemistry investigating novel therapeutic strategies for chronic inflammatory diseases.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of inflammation resolution, cellular signaling, and immune modulation.
• Drug Discovery & Development: Acts as a lead compound or molecular probe for developing new anti-inflammatory and pro-resolving therapeutics.
• In Vitro & In Vivo Studies: Employed in cell culture assays and animal models to elucidate the biological functions and mechanisms of action of lipoxins.
• Biochemical Pathway Analysis: Essential for studying eicosanoid metabolism, receptor-ligand interactions (e.g., with ALX/FPR2 receptors), and downstream signaling cascades.
• Academic & Institutional Research: A key reagent for universities and research institutes focused on immunology, molecular biology, and related life science fields.

Basic Information

Product Name	Lipoxin B4 Methyl Ester
CAS No.	97589-07-6
Molecular Formula	C22H32O6
Molecular Weight	392.49 g/mol
Synonyms	Lipoxin B4 Me ester; 5(S),14(R)-Dihydroxy-6,10,12(E),8(E)-eicosatetraenoic Acid Methyl Ester; LXB4 Methyl Ester; (5S,6R,15R)-Trihydroxy-7,9,13-trans-11-cis-eicosatetraenoic Acid Methyl Ester; Methyl (5S,6R,15R)-5,6,15-trihydroxyicosa-7,9,13-trans-11-cis-tetraenoate
EINECS	Contact for details

Quality Control

Our Lipoxin B4 Methyl Ester is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided to guarantee traceability and meet the exacting standards of the scientific community.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.