Description

Ademethionine Disulfate Tosylate is a high-purity, stabilized salt form of S-adenosylmethionine (SAMe), a critical biochemical cofactor. This compound is essential for its role in methylation, transsulfuration, and aminopropylation pathways within cellular metabolism. It is primarily utilized by pharmaceutical manufacturers and research institutions for the development of nutraceutical supplements and therapeutic agents targeting liver health, joint function, and mood regulation.

Application

• Pharmaceutical Intermediates: A key starting material or active pharmaceutical ingredient (API) in formulations for hepatoprotective and antidepressant drugs.
• Nutraceutical Supplements: Used in the production of high-grade dietary supplements aimed at supporting liver detoxification, joint mobility, and emotional well-being.
• Biochemical Research: Serves as a vital reagent in enzymatic studies, metabolic pathway analysis, and cellular biology research.
• Veterinary Medicine: Incorporated into animal health products for supporting liver function and overall metabolic health in livestock and companion animals.
• Cosmeceuticals: An active ingredient in advanced skincare formulations for its purported anti-aging and skin-rejuvenating properties.

Basic Information

Product Name	Ademethionine Disulfate Tosylate
CAS No.	97540-22-2
Molecular Formula	C15H23N6O5S2 • 2C7H8O3S • H2SO4
Molecular Weight	Contact for details
Synonyms	S-Adenosyl-L-methionine Disulfate Tosylate; SAMe Disulfate Tosylate; Ademetionine Disulfate Tosylate; AdoMet Disulfate Tosylate; SAM-e Tosylate Salt; (2S)-2-Amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylsulfonio]butanoate disulfate tosylate; A-9145C; Gumbaral; Gumbix
EINECS	Contact for details

Quality Control

Our Ademethionine Disulfate Tosylate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade standards suitable for pharmaceutical and nutraceutical applications. Certificates of Analysis (COA) documenting purity, heavy metals, residual solvents, and microbiological data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere such as nitrogen or argon for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Total Impurities (HPLC)	≤ 2.0%
Microbiological Analysis	Meets Ph. Eur. 2.6.12 & 2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.