Description

Troglitazone is a synthetic thiazolidinedione derivative that functions as a potent and selective agonist for the peroxisome proliferator-activated receptor gamma (PPARγ). This compound is of significant interest in pharmaceutical research and development due to its role as a foundational insulin sensitizer. It is primarily utilized by researchers and manufacturers in the life sciences sector for advanced metabolic studies and as a critical reference standard in analytical chemistry.

Application

• Pharmaceutical Reference Standard: Serves as a high-purity certified material for quality control (QC) and analytical method development in drug manufacturing and regulatory testing.
• Biochemical Research: Used as a potent PPARγ ligand in metabolic disease research, including studies on diabetes, insulin resistance, and adipogenesis.
• Mechanistic Studies: Employed to investigate the molecular pathways of insulin sensitization and the pharmacological effects of thiazolidinedione-class drugs.
• Active Pharmaceutical Ingredient (API) Intermediate: Acts as a key synthetic intermediate in the development and production of novel therapeutic agents targeting PPAR receptors.

Basic Information

Product Name	Troglitazone
CAS No.	97322-87-7
Molecular Formula	C₂₄H₂₇NO₅S
Molecular Weight	441.54 g/mol
Synonyms	5-[[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazolidinedione; (±)-Troglitazone; CS-045; Noscal; Prelay; Romozin; Rezulin
EINECS	Contact for details

Quality Control

Our Troglitazone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.