Description

Octreotide is a synthetic cyclic octapeptide analogue of the natural hormone somatostatin. This compound is a critical active pharmaceutical ingredient (API) valued for its potent inhibitory effects on the secretion of various hormones, including growth hormone, glucagon, and insulin. It is essential for the formulation of therapeutic drugs targeting conditions such as acromegaly, neuroendocrine tumors, and severe diarrhea. Pharmaceutical manufacturers and research institutions globally require high-purity Octreotide for the development and production of injectable medications.

Application

• Pharmaceutical API: Primary active ingredient in injectable formulations for treating acromegaly and gigantism.
• Oncological Therapeutics: Used in the management of symptoms from carcinoid syndrome and VIPomas (vasoactive intestinal peptide-secreting tumors).
• Gastroenterology: Treatment for severe, refractory diarrhea associated with conditions like AIDS or chemotherapy.
• Endocrine Disorder Management: Controls hormone over-secretion in various neuroendocrine disorders.
• Research & Development: Reference standard and key material in biochemical research, pharmacology studies, and new drug discovery.
• Veterinary Medicine: Potential application in treating similar endocrine conditions in animals.

Basic Information

Product Name	Octreotide
CAS No.	79517-01-4
Molecular Formula	C49H66N10O10S2
Molecular Weight	1019.24 g/mol
Synonyms	Octreotide Acetate; SMS 201-995; Sandostatin (brand name); D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2→7)-disulfide; Cyclo(L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinyl-D-phenylalanyl); Somatostatin Octapeptide Analogue
EINECS	Contact for details

Quality Control

Our Octreotide is manufactured under strict quality management systems to ensure it meets the highest standards for pharmaceutical use. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, identification by IR and MS, and stringent controls for related substances and residual solvents. We provide full traceability and support regulatory filings with comprehensive documentation. Certificates of Analysis (COA) confirming compliance with relevant pharmacopeial standards (e.g., USP, EP) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Bacterial Endotoxins	< 10.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.