Description

Vildagliptin is a highly selective and potent dipeptidyl peptidase-4 (DPP-4) inhibitor used as an active pharmaceutical ingredient (API). This compound is critical for the development and manufacture of oral anti-diabetic medications, offering a mechanism to improve glycemic control in patients with type 2 diabetes. It is primarily required by pharmaceutical manufacturers and research institutions engaged in metabolic disease therapeutics and novel drug formulation development.

Application

• Primary Active Pharmaceutical Ingredient (API) in oral anti-diabetic medications.
• Key component in the formulation of combination therapies for type 2 diabetes management.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Intermediate for research into next-generation DPP-4 inhibitors and related therapeutic agents.
• Biochemical research tool for studying the role of DPP-4 in metabolic and inflammatory pathways.

Basic Information

Product Name	Vildagliptin
CAS No.	274901-16-5
Molecular Formula	C17H25N3O2
Molecular Weight	303.40 g/mol
Synonyms	LAF237; NVP-LAF-237; (2S)-1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-pyrrolidinecarbonitrile; 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine; Galvus (brand name); Zomelis (brand name)
EINECS	Contact for details

Quality Control

Our Vildagliptin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and compliance with relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single unknown impurity ≤ 0.10%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.