Description

Insulin, Despentapeptide (B26-B30)-Phenh2(B25)- is a synthetic, biologically active insulin analogue designed for advanced research and development. This modified peptide is crucial for studying insulin receptor interactions, metabolic pathways, and the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on endocrinology and diabetes research.

Application

• Pharmaceutical Research & Development: As a key reference standard and active ingredient in the development of novel insulin-based therapeutics and delivery systems.
• Biochemical Studies: For investigating the structure-activity relationship (SAR) of insulin, its binding affinity to receptors, and downstream signaling mechanisms.
• Metabolic Disorder Research: Used in in vitro and in vivo models to study glucose metabolism, insulin resistance, and potential treatments for diabetes.
• Analytical Standard: Serves as a high-purity calibrant in HPLC, LC-MS, and other analytical methods for quality control and method validation in peptide analysis.
• Peptide Chemistry & Conjugation: Acts as a substrate for further chemical modification, labeling, or conjugation studies due to its specific structural alterations.

Basic Information

Product Name	Insulin, Despentapeptide (B26-B30)-Phenh2(B25)-
CAS No.	97123-35-8
Molecular Formula	C254H377N65O76S6
Molecular Weight	~5808.5 g/mol
Synonyms	Despentapeptide(B26-B30) Insulin; [Phe(B25)-NH2] Insulin; Insulin (human) Phe(B25)-NH2, Des-(B26-B30); Insulin analogue (B25-Phe-NH2, des-B26-B30); B25-Phenylalanine Amide Insulin; Insulin, Des-(B26-B30)-, B25-Phe-NH2; Modified Insulin B-Chain (1-25) Amide; Research Insulin Analogue 97123-35-8
EINECS	Contact for details

Quality Control

Our Insulin, Despentapeptide (B26-B30)-Phenh2(B25)- is manufactured under strict quality systems suitable for research applications. Each batch is characterized and tested to ensure high purity and structural integrity. Comprehensive analytical testing includes HPLC for purity, MS for identity confirmation, and peptide content determination. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure full traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Water Content (KF)	≤ 5.0%
Biological Activity	Assessed by in vitro assay (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.