Description

19,25-Dihydroxy-6,19-Dihydro-6,19-Epoxyvitamin D3 is a high-purity, synthetic vitamin D analog and a key intermediate in advanced pharmaceutical research. This compound is critical for developing novel therapeutic agents targeting vitamin D receptor pathways, offering significant potential in metabolic and bone disorder research. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in the synthesis of next-generation calcitriol analogs and related bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of advanced vitamin D analogs and metabolites with targeted biological activity.
• Biochemical Research: Used in studies investigating the structure-activity relationships (SAR) of vitamin D and its derivatives on cellular receptors.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in pharmaceutical analysis (HPLC, LC-MS).
• Drug Discovery: Employed in preclinical research for developing new therapeutic candidates for osteoporosis, psoriasis, and certain cancers.
• Metabolic Pathway Studies: Utilized to elucidate the complex metabolic pathways and enzymatic transformations of vitamin D3 in biological systems.

Basic Information

Item	Details
Product Name	19,25-Dihydroxy-6,19-Dihydro-6,19-Epoxyvitamin D3
CAS No.	96999-67-6
Molecular Formula	C27H42O4
Molecular Weight	430.62 g/mol
Synonyms	19,25-Dihydroxy-6,19-epoxyvitamin D3; 19,25-Dihydroxy-6,19-cyclovitamin D3; 6,19-Epoxy-19,25-dihydroxyvitamin D3; 1α,25-Dihydroxy-19,26-cyclo-9,10-secocholesta-5(10),6,8-trien-3β-ol (alternative systematic name); Vitamin D3 analog 96999-67-6; 19,25-(OH)2-6,19-cyclo-Vitamin D3
EINECS	Contact for details

Quality Control

Every batch of 19,25-Dihydroxy-6,19-Dihydro-6,19-Epoxyvitamin D3 is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and full analytical data is provided with each shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store unopened vials at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.