Description

(6E,22E)-(3R)-9,10-Secoergosta-5(10),6,8,22-Tetraen-3-Ol is a high-purity secosterol compound, a key intermediate in the synthesis of vitamin D analogs and other biologically active steroidal molecules. Its precise stereochemistry and defined double-bond geometry are critical for ensuring the efficacy and specificity of downstream pharmaceutical and research applications. This compound is essential for manufacturers and R&D laboratories in the pharmaceutical, nutraceutical, and fine chemical sectors requiring a reliable, high-quality building block for advanced synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active vitamin D metabolites (e.g., calcitriol) and novel vitamin D receptor modulators for therapeutic development.
• Research & Development: Used as a reference standard and starting material in academic and industrial research focused on steroid biochemistry, hormone action, and metabolic pathways.
• Nutraceutical Synthesis: Serves as an advanced intermediate in the production of high-value vitamin D supplements and related nutritional compounds.
• Fine Chemical Production: Employed in the multi-step synthesis of complex steroidal compounds for various life science applications.
• Biochemical Tool: Utilized in studies investigating the mechanisms of secosteroid formation and function.

Basic Information

Product Name	(6E,22E)-(3R)-9,10-Secoergosta-5(10),6,8,22-Tetraen-3-Ol
CAS No.	115-61-7
Molecular Formula	C₂₈H₄₄O
Molecular Weight	396.65 g/mol
Synonyms	Previtamin D3; (3R)-9,10-Seco-5(10),6,8(14),22-ergostatetraen-3-ol; Tachysterol3; (6E,22E)-(3R)-9,10-Secoergosta-5(10),6,8(14),22-tetraen-3-ol; 5,7,22-Ergostatrien-3β-ol; (3β,5E,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol (isomeric form); Provitamin D3 (common name for related isomers)
EINECS	204-098-6

Quality Control

Our (6E,22E)-(3R)-9,10-Secoergosta-5(10),6,8,22-Tetraen-3-Ol is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific customer or pharmacopeial (e.g., USP) requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.