Description

Menadiol Sodium Sulfate is a water-soluble, synthetic form of vitamin K. This compound is crucial as a precursor for the synthesis of menaquinone (vitamin K2) and is valued for its stability and bioavailability. It is primarily required by manufacturers in the pharmaceutical, nutraceutical, and animal feed industries for formulating vitamin supplements and addressing coagulation-related deficiencies.

Application

• Pharmaceutical Intermediates: A key starting material in the synthesis of various vitamin K analogs and active pharmaceutical ingredients (APIs).
• Dietary Supplements: Used in the production of vitamin K complex supplements for human nutrition, often in tablet or capsule form.
• Animal Feed Additives: Incorporated into premixes to prevent vitamin K deficiency and support proper blood clotting in livestock and poultry.
• Biochemical Research: Serves as a standard or reagent in studies related to coagulation pathways, bone metabolism, and vitamin K cycle.
• Cosmeceuticals: Explored for use in topical formulations aimed at improving skin health and reducing the appearance of dark circles.

Basic Information

Product Name	Menadiol Sodium Sulfate
CAS No.	1612-30-2
Molecular Formula	C11H8Na2O8S2 · xH2O
Molecular Weight	362.27 g/mol (Anhydrous)
Synonyms	Menadiol Diphosphate Tetrasodium Salt; Vitamin K4 Sodium Sulfate; 2-Methyl-1,4-naphthohydroquinone disodium sulfate; 1,4-Dihydroxy-2-methylnaphthalene bis(sodium sulfate); Menadiol bis(hydrogen sulfate) sodium salt; Menadiol sulfate sodium; Sodium menadiol sulfate
EINECS	216-565-9

Quality Control

Our Menadiol Sodium Sulfate is manufactured under a GMP-compliant quality management system. Each batch undergoes rigorous testing to ensure it meets stringent specifications for identity, purity, and potency. A comprehensive Certificate of Analysis (COA) documenting results for assay, related substances, residual solvents, and microbiological parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in its original packaging until use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to slightly yellow crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 8.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Microbiological Analysis	Total Aerobic Count ≤ 1000 cfu/g; Yeast & Mold ≤ 100 cfu/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.