Description

8β-Tigloyloxycostunolide is a high-purity sesquiterpene lactone derivative, a compound of significant interest in advanced research and development. Its unique molecular structure makes it a valuable intermediate and reference standard for exploring bioactive natural products. This compound is primarily utilized by research institutions and pharmaceutical development teams focused on anti-inflammatory, anticancer, and other therapeutic agent discovery programs.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel therapeutic agents.
• Bioactivity Screening: Used in in vitro and in vivo assays to investigate potential anti-inflammatory, cytotoxic, or antiproliferative properties.
• Natural Product Chemistry: Acts as a purified marker compound for the analysis and standardization of plant extracts containing sesquiterpene lactones.
• Chemical Synthesis: Employed as a sophisticated building block for the semi-synthesis of complex natural product analogs and derivatives.
• Academic Research: Utilized in university and institutional labs for mechanistic studies and structure-activity relationship (SAR) investigations.
• Analytical Standard: Provides a high-purity standard for method development and quantification in HPLC, LC-MS, and other analytical techniques.

Basic Information

Product Name	8β-Tigloyloxycostunolide
CAS No.	96850-21-4
Molecular Formula	C20H26O5
Molecular Weight	346.42 g/mol
Synonyms	8β-(2-Methyl-2-butenoyloxy)costunolide; 8β-Tigloyloxycostunolide; (8β)-8-[(2E)-2-Methyl-2-butenoyloxy]costunolide; Costunolide, 8β-(2-methyl-2-butenoate); 8β-Tigloyloxycostunolide (8β-TOC); Parthenolide derivative; Sesquiterpene lactone tiglate.
EINECS	Contact for details

Quality Control

Our 8β-Tigloyloxycostunolide is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storing at 2-8°C under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.