Description

1-o-Hexadecyl-2-Deoxy-2-Thio-S-Acetyl-Sn-Glyceryl-3-Phosphorylcholine is a high-purity synthetic phospholipid derivative, a critical building block in advanced pharmaceutical and biomedical research. This compound is valued for its role as a key intermediate in the synthesis of novel lipid-based drug delivery systems, such as liposomes and lipid nanoparticles (LNPs), which are essential for targeted and sustained-release therapies. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on innovative therapeutic formulations, including mRNA vaccines and cancer treatments.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of functionalized phospholipids for advanced drug delivery platforms.
• Liposome & Lipid Nanoparticle (LNP) Formulation: Used to create stable, targeted carriers for mRNA, siRNA, and other nucleic acid-based therapeutics.
• Biomembrane Research: Serves as a model compound for studying membrane biophysics, lipid rafts, and cell signaling pathways.
• Drug Discovery: Employed in the development of prodrugs and novel conjugates to enhance drug solubility, bioavailability, and targeting.
• Diagnostic Agent Development: Utilized in the creation of contrast agents and probes for medical imaging techniques.
• Cosmetic & Dermal Delivery Systems: Incorporated into nanocarrier systems for the topical delivery of active ingredients.

Basic Information

Product Name	1-o-Hexadecyl-2-Deoxy-2-Thio-S-Acetyl-Sn-Glyceryl-3-Phosphorylcholine
CAS No.	96801-55-7
Molecular Formula	C28H59N2O6PS
Molecular Weight	582.80 g/mol
Synonyms	1-Hexadecyl-2-deoxy-2-thioacetyl-sn-glycero-3-phosphocholine; S-Acetyl-1-O-hexadecyl-2-deoxy-2-thio-sn-glycero-3-phosphocholine; 1-O-Hexadecyl-2-S-acetyl-2-thio-sn-glycero-3-phosphocholine; Thioacetyl-PAF precursor; Thioacetyl Lyso-PAF analog; Phospholipid intermediate 96801-55-7; S-Acetyl thioether phospholipid
EINECS	Contact for details

Quality Control

Every batch of our 1-o-Hexadecyl-2-Deoxy-2-Thio-S-Acetyl-Sn-Glyceryl-3-Phosphorylcholine is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure it meets the exacting standards required for pharmaceutical R&D and production. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic purity data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The material is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.