Description

(8R,9S,10R,13S,14S)-10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-Dodecahydrospiro[Cyclopenta[A]Phenanthrene-17,2-[1,3]Dioxolan]-3(2H)-One (Wxg00896) is a high-purity, complex steroidal dioxolane derivative with significant value as a key synthetic intermediate. This compound is essential for researchers and manufacturers developing novel pharmaceutical agents, particularly in the fields of endocrinology and oncology. Its precise stereochemistry and functional groups make it a critical building block for advanced organic synthesis targeting hormone receptors and other biological pathways.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial R&D for exploring new chemical entities (NCEs) with potential biological activity, especially in cancer and metabolic disease research.
• Process Chemistry: Employed in process development and scale-up for the production of complex molecules, where its defined structure aids in route scouting and optimization.
• Biochemical Tool Compound: Utilized in biochemical assays to study steroid hormone pathways, enzyme inhibition, and receptor-ligand interactions.
• Fine Chemical Synthesis: Acts as a specialized building block for synthesizing other high-value, complex fine chemicals and custom molecules.

Basic Information

Item	Details
Product Name	(8R,9S,10R,13S,14S)-10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-Dodecahydrospiro[Cyclopenta[A]Phenanthrene-17,2-[1,3]Dioxolan]-3(2H)-One (Wxg00896)
CAS No.	1044-89-9
Molecular Formula	C22H32O3
Molecular Weight	344.49 g/mol
Synonyms	10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydrospiro[cyclopenta[a]phenanthrene-17,2'-[1,3]dioxolan]-3(2H)-one; Steroidal Dioxolane Derivative; WXG00896; 3-Oxo-17,2'-(1,3-dioxolanyl)-10,13-dimethyldodecahydrocyclopenta[a]phenanthrene; 1044-89-9; (8R,9S,10R,13S,14S)-10,13-Dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydrospiro[cyclopenta[a]phenanthrene-17,2'-[1,3]dioxolan]-3-one
EINECS	Contact for details

Quality Control

Every batch of our (8R,9S,10R,13S,14S)-10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-Dodecahydrospiro[Cyclopenta[A]Phenanthrene-17,2-[1,3]Dioxolan]-3(2H)-One is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.