Description

5-Androsten-3Beta-Ol-16Alpha-Fluoro-17-One is a high-purity fluorinated steroid derivative, also known as Fluoxymesterone Impurity A. This compound is of significant value as a key reference standard and synthetic intermediate in pharmaceutical research and development. It is primarily required by pharmaceutical manufacturers, analytical laboratories, and research institutions for quality control, method validation, and the synthesis of advanced steroid-based APIs.

Application

• Pharmaceutical Reference Standard: Used as a certified impurity standard for the analysis of Fluoxymesterone and related anabolic steroids.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical building block in the multi-step synthesis of fluorinated steroid hormones.
• Metabolic Pathway Research: Employed in biochemical studies to investigate steroid metabolism and transformation pathways.
• Analytical Method Development: Essential for developing and validating HPLC, LC-MS, and GC-MS methods in pharmaceutical QC labs.
• Process Chemistry: Used in process development and optimization for the commercial manufacture of steroid-based drugs.
• Academic & Institutional Research: A valuable reagent for universities and research centers studying steroid chemistry and endocrinology.

Basic Information

Product Name	5-Androsten-3Beta-Ol-16Alpha-Fluoro-17-One
CAS No.	1649-27-0
Molecular Formula	C19H29FO2
Molecular Weight	308.43 g/mol
Synonyms	Fluoxymesterone Impurity A; 16α-Fluoro-5-androsten-3β-ol-17-one; 16α-Fluoroandrost-5-ene-3β,17β-diol-17-one; 9α-Fluoro-11β,17β-dihydroxy-17α-methylandrost-4-en-3-one Impurity; Androst-5-ene-3β,17β-diol, 16α-fluoro-, 17-one; 16α-Fluoro-3β-hydroxyandrost-5-en-17-one
EINECS	Contact for details

Quality Control

Our 5-Androsten-3Beta-Ol-16Alpha-Fluoro-17-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC purity assay, identity confirmation (IR, NMR), and specific impurity profiling to ensure it meets the stringent requirements for use as a reference material. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.