Description

2,5-Piperazinedicarboxylicacid,cis-(9Ci) is a specialized heterocyclic dicarboxylic acid derivative, a key chiral building block in advanced organic synthesis. This compound matters for its role as a rigid, functionalized piperazine scaffold, enabling the construction of complex molecules with precise stereochemistry. Pharmaceutical researchers and fine chemical manufacturers need it for developing active pharmaceutical ingredients (APIs), particularly in medicinal chemistry for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel APIs, especially in central nervous system (CNS) and antiviral drug candidates.
• Ligand Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis, enhancing the efficiency and selectivity of chemical transformations.
• Peptidomimetics: Serves as a constrained, non-natural amino acid analog in the design of peptide mimetics to improve metabolic stability and bioavailability.
• Coordination Chemistry: Acts as a chelating agent for metal ions, useful in creating metal-organic frameworks (MOFs) or catalysts.
• Polymer Chemistry: A monomer for synthesizing specialty polyamides and polyimides with unique thermal and mechanical properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis and process chemistry within university and corporate laboratories.

Basic Information

Product Name	2,5-Piperazinedicarboxylicacid,cis-(9Ci)
CAS No.	96705-91-8
Molecular Formula	C6H10N2O4
Molecular Weight	174.16 g/mol
Synonyms	(2S,5S)-Piperazine-2,5-dicarboxylic acid; cis-2,5-Piperazinedicarboxylic Acid; (2S,5S)-2,5-Dicarboxypiperazine; L,L-cis-2,5-Diaminopiperazine-2,5-dicarboxylic acid; (2S,5S)-Hexahydropyrazine-2,5-dicarboxylic acid; 2,5-Dicarboxypiperazine (cis isomer); (S,S)-2,5-Piperazinedicarboxylic acid
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedicarboxylicacid,cis-(9Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), chiral purity, and impurity profiles. Specifications can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.