Description

Insulin, Arg(B31)- is a specific, chemically modified analog of human insulin, identified by CAS No. 96351-10-9. This engineered peptide is of significant interest in advanced pharmaceutical research and development, particularly for studying insulin receptor interactions and metabolic pathways. It serves as a critical intermediate or reference standard for scientists and manufacturers in the biopharmaceutical sector focused on next-generation diabetes therapies and metabolic disorder research.

Application

• Pharmaceutical R&D Intermediate: Used as a key building block in the research and synthesis of novel insulin analogs and peptide-based therapeutics.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in peptide and biopharmaceutical analysis.
• Biochemical Research: Employed in academic and industrial laboratories to study insulin signaling, receptor binding affinity, and structure-activity relationships (SAR).
• Metabolic Studies: Utilized in preclinical research to investigate the effects of specific insulin modifications on glucose metabolism and pharmacokinetics.
• Process Development: Acts as a model compound for developing and optimizing purification, formulation, and stability testing processes for peptide APIs.

Basic Information

Product Name	Insulin, Arg(B31)-
CAS No.	96351-10-9
Molecular Formula	C257H383N65O77S6
Molecular Weight	5807.9 g/mol (approx.)
Synonyms	Arg(B31)-Insulin; [ArgB31]-Insulin; Insulin (human) Arg(B31) analog; B31-Arginine Insulin; Insulin analog B31-Arg; Insulin, ArgB31-; Human Insulin Arg(B31) variant; 96351-10-9
EINECS	Contact for details

Quality Control

Our Insulin, Arg(B31)- is produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and peptide mapping for identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data and specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Water Content (KF)	≤ 10.0%
Peptide Content	≥ 80.0%
Biological Activity	Assessed by specific assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.