Description

3A,4,5,6,6A,9,9A,9B-Octahydro-6,6A,9-Trihydroxy-6,9-Dimethyl-3-Methyleneazuleno[4,5-B]Furan-2(3H)-One is a complex sesquiterpene lactone derivative with a unique azulene-fused furanone structure. This compound is valued as a high-purity advanced intermediate for the synthesis of novel bioactive molecules in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new chemical entities with potential therapeutic or biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in anti-inflammatory and anticancer research.
• Organic Synthesis Research: Used in academic and industrial laboratories to explore new chemical reactions and construct complex natural product analogs.
• Agrochemical Development: Serves as a precursor for developing new active ingredients with potential herbicidal or pesticidal properties.
• Material Science: Investigated as a monomer or specialty additive for creating polymers with unique optical or electronic characteristics.
• Biochemical Probe: Utilized in life sciences research to study biological pathways and enzyme interactions due to its specific structural motifs.

Basic Information

Item	Details
Product Name	3A,4,5,6,6A,9,9A,9B-Octahydro-6,6A,9-Trihydroxy-6,9-Dimethyl-3-Methyleneazuleno[4,5-B]Furan-2(3H)-One
CAS No.	96154-30-2
Molecular Formula	C15H20O5
Molecular Weight	280.32 g/mol
Synonyms	6,6A,9-Trihydroxy-6,9-dimethyl-3-methylenepentacyclo[6.5.0.0²,⁵.0³,¹⁰.0⁸,¹²]tridecane-4,11-dione; Azuleno[4,5-b]furan-2(3H)-one derivative; (3aS,6R,6aR,9R,9aS,9bR)-6,6a,9-Trihydroxy-6,9-dimethyl-3-methylidene-3a,4,5,6,6a,9,9a,9b-octahydroazuleno[4,5-b]furan-2-one; Sesquiterpene lactone intermediate; Advanced azulene-furanone synthon.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and MS. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.