Description

Meropenem is a broad-spectrum, β-lactam carbapenem antibiotic belonging to the thienamycin class. It is a critical pharmaceutical active ingredient valued for its efficacy against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, including many multi-drug resistant strains. This makes it an essential component in the formulation of injectable antibiotics for the treatment of severe hospital-acquired infections such as meningitis, intra-abdominal infections, and complicated skin structure infections. Pharmaceutical manufacturers and compounding facilities globally rely on high-purity Meropenem CAS NO 96036-03-2 for producing sterile injectable formulations.

Application

Meropenem is exclusively used as a potent antibacterial agent in human medicine. Its primary applications include:

• Active Pharmaceutical Ingredient (API): Core component in the manufacture of sterile injectable antibiotic formulations.
• Treatment of Severe Bacterial Infections: Used in hospitals for empiric and targeted therapy of life-threatening infections including nosocomial pneumonia, septicemia, and febrile neutropenia.
• Management of Multi-Drug Resistant (MDR) Infections: Critical for infections caused by bacteria resistant to penicillins, cephalosporins, and other β-lactam antibiotics.
• Surgical Prophylaxis and Treatment: Employed for perioperative prophylaxis and treatment of post-surgical intra-abdominal and complicated skin/soft tissue infections.
• Pediatric and Adult Formulations: Used in developing dosage forms suitable for both adult and pediatric patient populations.
• Compassionate Use and Clinical Trials: Serves as a key agent in clinical research for new antibacterial therapies and in special access programs.

Basic Information

Product Name	Meropenem
CAS No.	96036-03-2
Molecular Formula	C17H25N3O5S
Molecular Weight	383.46 g/mol
Synonyms	Meropenem Trihydrate; SM-7338; ICI-194660; (4R,5S,6S)-3-[[(3S,5S)-5-(Dimethylcarbamoyl)-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid; Meronem; Merrem; Meropenemum; Meropenem Anhydrous
EINECS	Contact for details

Quality Control

Our Meropenem is manufactured under strict quality systems designed for pharmaceutical active ingredients. Quality control adheres to current Good Manufacturing Practices (cGMP) and relevant pharmacopeial standards (USP, EP, JP). Each batch undergoes comprehensive testing including identification, assay, impurity profiling, residual solvents, and microbiological analysis. A Certificate of Analysis (COA) documenting all test results against stringent specifications is provided with every shipment to ensure traceability and regulatory compliance for our global customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature between 15°C and 25°C (59°F and 77°F). This product is hygroscopic (moisture-sensitive) and must be protected from exposure to high humidity. For long-term stability, storage under an inert atmosphere such as nitrogen is recommended.

Specification

Item	Specification
Appearance	White to slightly yellowish crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Bacterial Endotoxins	< 0.17 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.