Description

Swinholide A CAS NO 95927-67-6 is a potent, naturally occurring macrodiolide compound originally isolated from marine sponges. This compound is of significant interest in biochemical and pharmacological research due to its unique mechanism of action as a potent actin-depolymerizing agent. It serves as a critical research tool for scientists in oncology, cell biology, and drug discovery, enabling the study of cytoskeletal dynamics and the development of novel therapeutic strategies.

Application

• Biochemical Research: Used as a highly specific and potent probe to study actin filament dynamics, cell motility, and morphology.
• Oncology Research: Investigated for its cytotoxic properties and potential as a lead compound in the development of novel anti-cancer agents.
• Cell Biology Studies: Essential for research involving the cytoskeleton, including processes like cytokinesis, intracellular transport, and cell signaling.
• Pharmacology & Drug Discovery: Serves as a reference standard and a molecular tool for high-throughput screening and mechanism-of-action studies.
• Marine Natural Product Research: A reference compound for the study of bioactive metabolites derived from marine organisms.

Basic Information

Product Name	Swinholide A
CAS No.	95927-67-6
Molecular Formula	C₅₄H₈₄O₁₅
Molecular Weight	965.24 g/mol
Synonyms	Swinholide A; 30-O-Demethylswinholide A; Swinholide; (1R,2R,4S,5S,7R,8R,10S,11S,13R,14R,16S,17S,19R,20R,22S,23S,25R,26R,28S,29S,31R,32R,34S,35S,37R,38R,40S,41S,43R,44R,46S,47S,49R,50R,52S,53S)-1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53-Hexatriacontaoxacyclooctapentacontane-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54-octadecanone
EINECS	Contact for details

Quality Control

Our Swinholide A is produced under strict quality management protocols to ensure the highest standards of purity and consistency for research applications. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment to guarantee traceability and reliability for your research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Due to its hygroscopic nature, the container should be allowed to reach room temperature before opening to minimize moisture absorption. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.