Description

11,12-Epoxypukalide is a specialized diterpenoid compound of significant interest in advanced chemical research and development. Its unique epoxide functional group and complex molecular architecture make it a valuable intermediate for synthesizing novel bioactive molecules. This high-purity compound is primarily sought by research institutions and pharmaceutical developers working on new therapeutic agents and biochemical probes.

Application

• Pharmaceutical Research Intermediate: Serves as a key synthetic building block for the development of new drug candidates, particularly in oncology and anti-inflammatory research.
• Biochemical Probe Development: Used in studying biological pathways and enzyme interactions due to its specific reactive epoxide moiety.
• Natural Product Synthesis: Acts as a crucial intermediate in the total synthesis of complex natural products and their analogs for structure-activity relationship (SAR) studies.
• Academic & Industrial R&D: Employed in chemical biology and medicinal chemistry programs within university laboratories and corporate R&D centers.
• Reference Standard: Provides a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	11,12-Epoxypukalide
CAS No.	95925-22-7
Molecular Formula	C20H28O5
Molecular Weight	348.43 g/mol
Synonyms	11,12-Epoxy-13,14,15,16-tetranorpukalide; Pukalide, 11,12-epoxy-; 11,12-Epoxypukalide; (1R,4R,4aS,7R,7aS,8S,9aR)-8-[(2S)-3,3-Dimethyloxiran-2-yl]-4,7-dimethyl-1-propan-2-yl-2,3,4a,5,7,7a,8,9-octahydro-1H-4,9a-methanocyclohepta[b]furan-6-one
EINECS	Contact for details

Quality Control

Our 11,12-Epoxypukalide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable for pharmaceutical intermediates, and our analytical methods are validated to meet rigorous scientific standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.