Description

3,6,7,12-Tetrahydroxycholestanoic Acid is a hydroxylated bile acid derivative, a key intermediate in the study of cholesterol metabolism and bile acid synthesis pathways. This compound matters for its role in advanced biochemical research, particularly in investigating liver function, cholestasis, and metabolic disorders. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of high-purity biochemical standards and reference materials.

Application

• Biochemical Research: Critical intermediate for studying bile acid biosynthesis, cholesterol catabolism, and related metabolic pathways.
• Pharmaceutical Development: Used as a reference standard and synthetic precursor in the development of therapeutics targeting liver diseases and metabolic syndromes.
• Diagnostic Reagents: Serves as a calibrant or component in the development of diagnostic assays for detecting bile acid disorders.
• Metabolomics Studies: Employed as an analytical standard in LC-MS and GC-MS platforms for the accurate quantification of bile acid profiles in biological samples.
• Enzymology Studies: Substrate or inhibitor for research on enzymes involved in steroid and bile acid metabolism, such as hydroxylases and dehydrogenases.

Basic Information

Product Name	3,6,7,12-Tetrahydroxycholestanoic Acid
CAS No.	95889-31-9
Molecular Formula	C₂₇H₄₆O₆
Molecular Weight	466.65 g/mol
Synonyms	3α,6α,7α,12α-Tetrahydroxy-5β-cholestan-26-oic Acid; 5β-Cholestane-3α,6α,7α,12α-tetrol-26-oic Acid; Tetrahydroxycholestanoic Acid; (25R)-3α,6α,7α,12α-Tetrahydroxy-5β-cholestan-26-oic Acid; 3,6,7,12-Tetrahydroxy-5β-cholestan-26-oic Acid; 5β-Cholestane-26-oic-3α,6α,7α,12α-tetrol
EINECS	Contact for details

Quality Control

Our 3,6,7,12-Tetrahydroxycholestanoic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); ensure the container is sealed under inert atmosphere or with desiccant after opening to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.