Description

1-(2,3-Dihydro-Benzo[1,4]Dioxine-6-Sulfonyl)-Piperazine is a high-purity sulfonamide-based piperazine derivative, serving as a critical pharmaceutical intermediate and organic building block for advanced synthesis. Its unique molecular structure, featuring a benzo[1,4]dioxine moiety, makes it a valuable precursor for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides due to its sulfonamide functionality.
• Ligand and Catalyst Development: Serves as a precursor for creating complex ligands used in catalytic processes and material science.
• Organic Synthesis Research: A versatile reagent for constructing complex heterocyclic compounds in academic and industrial R&D laboratories.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	1-(2,3-Dihydro-Benzo[1,4]Dioxine-6-Sulfonyl)-Piperazine
CAS No.	95591-73-4
Molecular Formula	C12H16N2O4S
Molecular Weight	284.33 g/mol
Synonyms	1-(2,3-Dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine; 1-(1,4-Benzodioxan-6-ylsulfonyl)piperazine; 6-(Piperazine-1-sulfonyl)-2,3-dihydro-1,4-benzodioxine; Piperazine, 1-[(2,3-dihydro-1,4-benzodioxin-6-yl)sulfonyl]-; 1,4-Benzodioxane-6-sulfonylpiperazine; Benzo[1,4]dioxine-6-sulfonyl piperazine; 95591-73-4
EINECS	Contact for details

Quality Control

Our 1-(2,3-Dihydro-Benzo[1,4]Dioxine-6-Sulfonyl)-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.