Description

2,3-Dibromopyrazine is a versatile and high-purity brominated heterocyclic building block essential for advanced organic synthesis. Its primary value lies in serving as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for introducing bromine functionality into pyrazine scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other nitrogen-containing heterocyclic therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides where the pyrazine core imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl and other complex structures.
• Chemical Library Production: Used in parallel and combinatorial chemistry within contract research organizations (CROs) to generate diverse compound libraries for screening.

Basic Information

Item	Detail
Product Name	2,3-Dibromopyrazine
CAS No.	95538-03-7
Molecular Formula	C4H2Br2N2
Molecular Weight	237.88 g/mol
Synonyms	2,3-Dibromopyrazine; Pyrazine, 2,3-dibromo-; Dibromopyrazine; 2,3-Dibromo-1,4-diazine; 2,3-Dibromopyrazine (major); 95538-03-7 (CAS); 2,3-Dibromo-pyrazine
EINECS	Contact for details

Quality Control

Our 2,3-Dibromopyrazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and scale-up. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.