Description

2-(3-Fluorophenoxy)Acetyl Chloride is a high-purity, reactive organic intermediate essential for constructing complex molecular architectures. Its value lies in its role as a versatile acylating agent, enabling the efficient synthesis of amides and esters under controlled conditions. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the production of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aryl ether motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the 3-fluorophenoxy group confers specific biological activity.
• Peptide Mimetics & Modifications: Employed as an acyl chloride reagent for introducing the 2-(3-fluorophenoxy)acetyl group onto amino acids or peptides.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Chemical Research & Development: A valuable reagent for academic and industrial labs exploring new synthetic methodologies and fluorinated compounds.
• Liquid Crystal & OLED Material Precursor: Used in the synthesis of fluorinated components for electronic display and lighting applications.

Basic Information

Product Name	2-(3-Fluorophenoxy)Acetyl Chloride
CAS No.	95299-69-7
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	2-(3-Fluorophenoxy)acetyl chloride; 3-Fluorophenoxyacetyl chloride; Acetyl chloride, 2-(3-fluorophenoxy)-; 2-(3-Fluorophenoxy)ethanoyl chloride; (3-Fluorophenoxy)acetic acid chloride; α-Chloro-3'-fluoroacetophenone ether; 95299-69-7; NSC 405124
EINECS	Contact for details

Quality Control

Our 2-(3-Fluorophenoxy)Acetyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and reactive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.