Description

1,24-Dihydroxy-22-Dehydrovitamin D3 is a biologically active vitamin D analog, representing a key intermediate and reference standard in advanced pharmaceutical research and development. This compound is critical for studying the metabolic pathways and therapeutic potential of vitamin D derivatives, particularly in relation to calcium regulation and cell differentiation. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers focused on endocrinology, oncology, and metabolic disease therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel vitamin D-based therapeutics and prodrugs.
• Biochemical Research: Used as a high-purity reference standard in metabolic studies, receptor binding assays, and pathway analysis.
• Drug Discovery & Development: A key compound for screening and developing new agents targeting vitamin D receptors (VDR) for cancer and autoimmune diseases.
• Analytical Standard: Essential for method development, validation, and quality control (QC) in analytical laboratories using HPLC, LC-MS, or NMR.
• Nutraceutical Research: Investigated for potential applications in advanced dietary supplements targeting bone health and immune support.

Basic Information

Product Name	1,24-Dihydroxy-22-Dehydrovitamin D3
CAS No.	95270-41-0
Molecular Formula	C27H42O3
Molecular Weight	414.62 g/mol
Synonyms	1,24-Dihydroxy-22-dehydrocholecalciferol; 22-Dehydro-1,24-dihydroxyvitamin D3; (5Z,7E)-9,10-Secocholesta-5,7,10(19),22-tetraene-1,3,24-triol; 1α,24-Dihydroxy-22-dehydrovitamin D3; Vitamin D3 analog 1,24-(OH)2-22-dehydro; EB 1089 related compound; Secalciferol derivative
EINECS	Contact for details

Quality Control

Our 1,24-Dihydroxy-22-Dehydrovitamin D3 is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated) or as indicated on the label or COA. For long-term storage, consider keeping the product under an inert atmosphere at -20°C or below. The container should be kept in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.