Description

(5S)-5,5A,6,7,8,9Bα-Hexahydro-5α,8β-Dihydroxy-3,5Aα,9-Trimethylnaphtho[1,2-B]Furan-2(4H)-One is a high-purity, complex furanone derivative with a defined stereochemistry, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in its unique polycyclic structure and functional groups, which enable precise chemical transformations for creating sophisticated target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for complex, stereospecific drug candidates.
• Fine Chemical Synthesis: Used as a sophisticated building block for constructing complex natural product analogs and other high-value specialty organic compounds.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development and testing of new asymmetric catalytic methodologies.
• Process Chemistry Development: Serves as a critical intermediate in scaling up synthetic routes from laboratory to pilot and commercial production scales.
• Academic & Industrial R&D: A valuable compound for chemical research in universities and corporate R&D centers focused on synthetic methodology and medicinal chemistry.

Basic Information

Product Name	(5S)-5,5A,6,7,8,9Bα-Hexahydro-5α,8β-Dihydroxy-3,5Aα,9-Trimethylnaphtho[1,2-B]Furan-2(4H)-One
CAS No.	95262-46-7
Molecular Formula	C₁₇H₂₄O₄
Molecular Weight	292.37 g/mol
Synonyms	5α,8β-Dihydroxy-3,5aα,9-trimethyl-5,5a,6,7,8,9bα-hexahydronaphtho[1,2-b]furan-2(4H)-one; (5S)-Hexahydro-5a,8b-dihydroxy-3,5aa,9-trimethylnaphtho[1,2-b]furan-2(4H)-one; Naphtho[1,2-b]furan-2(4H)-one derivative; Complex Furanone Intermediate; Chiral Furanone Building Block
EINECS	Contact for details

Quality Control

Our (5S)-5,5A,6,7,8,9Bα-Hexahydro-5α,8β-Dihydroxy-3,5Aα,9-Trimethylnaphtho[1,2-B]Furan-2(4H)-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical and fine chemical intermediates. Certificates of Analysis (COA) detailing specific results for purity, chiral purity, and impurities are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.