Description

3-Methyl-2-Thienylmagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, widely used in synthetic organic chemistry. Its primary value lies in its ability to act as a powerful nucleophile for the formation of carbon-carbon bonds, enabling the synthesis of complex thiophene-containing molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require a reliable building block for heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) containing functionalized thiophene rings.
• Agrochemical Synthesis: Used to create novel thiophene-based compounds for crop protection agents and herbicides.
• Material Science: Employed in the development of organic semiconductors, conductive polymers, and other advanced electronic materials.
• Fine Chemical Production: Serves as a versatile reagent for the custom synthesis of complex organic molecules in research and development.
• Cross-Coupling Reactions: Acts as a coupling partner in palladium-catalyzed reactions (e.g., Kumada coupling) to form biaryl structures.
• Nucleophilic Addition: Reacts with carbonyl compounds (aldehydes, ketones, esters) to form new alcohols and carboxylic acid derivatives.

Basic Information

Item	Details
Product Name	3-Methyl-2-Thienylmagnesium Bromide
CAS No.	95184-07-9
Molecular Formula	C5H5BrMgS
Molecular Weight	201.36 g/mol
Synonyms	3-Methyl-2-thienylmagnesium bromide; 3-Methylthiophen-2-ylmagnesium bromide; (3-Methyl-2-thienyl)magnesium bromide; 3-Methyl-2-thiophenemagnesium bromide; Magnesium, bromo(3-methyl-2-thienyl)-; 2-Thienylmagnesium bromide, 3-methyl-; Grignard reagent 3-methyl-2-thienyl
EINECS	Contact for details

Quality Control

Our 3-Methyl-2-Thienylmagnesium Bromide is produced under stringent quality management protocols. Each batch undergoes rigorous analytical testing, including titration for Grignard concentration and GC/HPLC analysis for purity and solvent content, to ensure consistency and reliability for your synthetic applications. A comprehensive Certificate of Analysis (COA) detailing concentration, assay, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For extended stability, storage at 2-8°C is recommended. Always handle and transfer the reagent under an inert atmosphere using standard Schlenk line or glovebox techniques.

Specification

Item	Specification
Appearance	Clear to slightly colored solution
Concentration (in THF or Ether)	0.5 M - 2.0 M (Custom concentrations available)
Assay (by Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.