Description

3,4-Dimethoxybenzylmagnesium Chloride is a versatile organometallic reagent, specifically a Grignard reagent, widely used in synthetic organic chemistry for the formation of carbon-carbon bonds. Its primary value lies in its ability to introduce the 3,4-dimethoxybenzyl group into target molecules, a key structural motif in the development of pharmaceuticals and advanced materials. This high-purity reagent is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable and consistent building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing substituted benzyl or phenethylamine structures.
• Agrochemical Development: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Material Science: Employed in the synthesis of specialty chemicals, liquid crystals, and organic electronic materials.
• Academic and Industrial R&D: Serves as a critical reagent in method development and exploratory synthesis for novel organic compounds.
• Cross-Coupling Reactions: Acts as a nucleophile in various transition-metal catalyzed coupling reactions to construct complex molecular architectures.
• Asymmetric Synthesis: Utilized in the preparation of chiral intermediates for enantioselective synthesis pathways.

Basic Information

Product Name	3,4-Dimethoxybenzylmagnesium Chloride
CAS No.	108071-30-3
Molecular Formula	C9H11ClMgO2
Molecular Weight	210.93 g/mol
Synonyms	3,4-Dimethoxybenzylmagnesium Chloride; (3,4-Dimethoxyphenyl)methylmagnesium Chloride; 3,4-Dimethoxybenzyl Grignard Reagent; Magnesium, chloromethylbis(3,4-dimethoxyphenyl)-; Veratrylmagnesium Chloride; 1-(Chloromagnesio)methyl-3,4-dimethoxybenzene; 3,4-Dimethoxybenzylmagnesium Chloride solution
EINECS	Contact for details

Quality Control

Our 3,4-Dimethoxybenzylmagnesium Chloride is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm identity, purity, and concentration (typically supplied as a solution in THF or diethyl ether). We provide comprehensive Certificates of Analysis (COA) detailing assay, titration results, and solvent content. Our quality management system supports compliance with cGMP and ISO standards for reliable sourcing in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is highly volatile and easily oxidized. Keep away from heat, sparks, open flames, and incompatible materials such as moisture, acids, and oxidizing agents. Use only in a well-ventilated area or fume hood.

Specification

Item	Specification
Appearance	Clear, colorless to light yellow solution
Identification (IR)	Conforms to structure
Assay (Titration)	0.5 M in THF (or as specified)
Purity (GC/HPLC)	≥ 95% (on an anhydrous solvent-free basis)
Solvent	THF or Diethyl Ether

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.