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1,3-Diarachidonoyl Glycerol CAS NO 95034-09-6
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CAS No.:95034-09-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1,3-Diarachidonoyl Glycerol is a specialized diacylglycerol (DAG) derivative where arachidonic acid is esterified at the sn-1 and sn-3 positions of the glycerol backbone. This compound is a critical biochemical intermediate and signaling molecule, playing a significant role in lipid metabolism and cellular signal transduction pathways. It is essential for researchers and manufacturers in the fields of lipidomics, pharmaceutical development, and biochemical research, particularly for studying second messenger systems, enzyme kinetics, and metabolic disorders.
Application
- Biochemical Research & Lipidomics: Serves as a high-purity standard and substrate for studying diacylglycerol kinases, protein kinase C (PKC) isoforms, and other lipid-mediated signaling cascades.
- Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and development of lipid-based therapeutics and diagnostic assays.
- Cell Biology Studies: Applied in cellular models to investigate the role of specific DAG species in membrane dynamics, vesicle trafficking, and apoptosis.
- Enzymology: Acts as a specific substrate for lipases, phospholipases, and other lipid-modifying enzymes to determine activity and inhibition.
- Metabolic Pathway Analysis: Utilized in tracer studies to elucidate the biosynthesis and turnover of complex lipids containing arachidonic acid.
- Nutritional Science: Investigated for its metabolic effects and potential implications in dietary lipid research.
Basic Information
| Item | Details |
|---|---|
| Product Name | 1,3-Diarachidonoyl Glycerol |
| CAS No. | 95034-09-6 |
| Molecular Formula | C₄₃H₆₈O₅ |
| Molecular Weight | 665.0 g/mol |
| Synonyms | 1,3-Di(5Z,8Z,11Z,14Z-eicosatetraenoyl)-rac-glycerol; 1,3-Bis(5Z,8Z,11Z,14Z-eicosatetraenoyl)glycerol; rac-1,3-Diarachidonoylglycerol; DAG(20:4/0:0/20:4); 1,3-Di(5,8,11,14-eicosatetraenoyl)glycerol; AA-DAG; Diacylglycerol containing arachidonic acid |
| EINECS | Contact for details |
Quality Control
Our 1,3-Diarachidonoyl Glycerol is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assessment and structural confirmation, to ensure it meets the exacting standards required for research and reference applications. A detailed Certificate of Analysis (COA) providing batch-specific data on purity, identity, and impurities is supplied with every shipment.
Storage
Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow oil or solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% (Area %) |
| Water Content (KF) | ≤ 0.5% |
| Heavy Metals | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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