Description

1-(4-Bromobenzoyl)Piperazine-2,3-Dicarboxylic Acid is a high-purity, multifunctional piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and versatile intermediate for constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require specific stereochemistry for optimal activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetic Research: The piperazine-2,3-dicarboxylic acid core is integral for designing and synthesizing peptidomimetics and conformationally constrained peptides.
• Chemical Biology Probes: Employed in the creation of specialized chemical probes for studying enzyme mechanisms and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Item	Details
Product Name	1-(4-Bromobenzoyl)Piperazine-2,3-Dicarboxylic Acid
CAS No.	94856-92-5
Molecular Formula	C14H15BrN2O5
Molecular Weight	371.19 g/mol
Synonyms	1-[(4-Bromophenyl)carbonyl]piperazine-2,3-dicarboxylic acid; (2S,3S)-1-(4-Bromobenzoyl)piperazine-2,3-dicarboxylic acid; 4-Bromobenzoyl-piperazine-2,3-dicarboxylic Acid; 2,3-Piperazinedicarboxylic acid, 1-(4-bromobenzoyl)-; L-Piperazine-2,3-dicarboxylic acid 1-(4-bromobenzoyl) derivative; (2S,3S)-1-(p-Bromobenzoyl)piperazine-2,3-dicarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(4-Bromobenzoyl)Piperazine-2,3-Dicarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.