Description

4-[(S)-2-[(1R,3R,5S)-3,5-Dimethyl-2-Oxocyclohexyl]-2-Hydroxyethyl]-2,6-Piperidinedione is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in oncology and other therapeutic areas. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of proprietary drug candidates.
• Oncology Research: Used in the development of targeted cancer therapies and chemotherapeutic agents.
• Process Chemistry & Scale-Up: Serves as a validated starting material for process optimization and commercial-scale API manufacturing under GMP guidelines.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	4-[(S)-2-[(1R,3R,5S)-3,5-Dimethyl-2-Oxocyclohexyl]-2-Hydroxyethyl]-2,6-Piperidinedione
CAS No.	94799-82-3
Molecular Formula	C15H23NO4
Molecular Weight	281.35 g/mol
Synonyms	(3S)-3-[2-[(1R,3R,5S)-3,5-Dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione; 4-[(1S)-2-[(1R,3R,5S)-3,5-Dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-2,6-piperidinedione; Thalidomide analog intermediate; Cyclohexanone, 2-[2-hydroxy-2-[(2S)-2,6-dioxo-3-piperidinyl]ethyl]-4,6-dimethyl-, (1R,3R,5S)-
EINECS	Contact for details

Quality Control

Our 4-[(S)-2-[(1R,3R,5S)-3,5-Dimethyl-2-Oxocyclohexyl]-2-Hydroxyethyl]-2,6-Piperidinedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure compliance with client specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.