Description

1,3,4,14B-Tetrahydro-2,7-Dimethyl-2H-Dibenzo[B,F]Pyrazino[1,2-D][1,4]Oxazepine Monohydrochloride is a high-purity, complex heterocyclic compound with significant value as a key pharmaceutical intermediate or reference standard. This compound matters for its role in advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel psychotropic or neuroactive drug candidates.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical manufacturing.
• Biochemical Research: Serves as a tool compound for studying receptor binding affinity and pharmacological activity in preclinical studies.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex molecular entities.
• Academic Research: Utilized in universities and research institutes for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Impurity Standard: Acts as a certified reference material for identifying and quantifying related substances in final API batches.

Basic Information

Product Name	1,3,4,14B-Tetrahydro-2,7-Dimethyl-2H-Dibenzo[B,F]Pyrazino[1,2-D][1,4]Oxazepine Monohydrochloride
CAS No.	94713-27-6
Molecular Formula	C19H21N3O•HCl
Molecular Weight	335.85 g/mol (Free base: 299.39 g/mol)
Synonyms	2,7-Dimethyl-1,3,4,14b-tetrahydro-2H-dibenzo[b,f]pyrazino[1,2-d][1,4]oxazepine hydrochloride; Loxapine Impurity; Loxapine Related Compound; 8-Chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,5]benzoxazepine (Parent compound derivative); Dibenzoxazepine derivative; AD-4033 (Potential research code); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1,3,4,14B-Tetrahydro-2,7-Dimethyl-2H-Dibenzo[B,F]Pyrazino[1,2-D][1,4]Oxazepine Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing comprehensive test results, including assay and impurity profiles by HPLC, are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.