Description

Senkyunolide H CAS NO 94596-27-7 is a bioactive phthalide compound, a key marker constituent found in the traditional Chinese medicinal herb *Ligusticum chuanxiong* Hort. (Chuanxiong). Its significance lies in its potent pharmacological activities, which are of high interest for research and development in modern therapeutics. This compound is primarily needed by research institutions, pharmaceutical companies, and nutraceutical developers focusing on cardiovascular health, neuroprotection, and anti-inflammatory applications.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and standardization of herbal extracts and finished products containing *Ligusticum chuanxiong*.
• Biomedical Research: Serves as a critical tool for in vitro and in vivo studies investigating mechanisms related to vasodilation, antiplatelet aggregation, and cerebral ischemia-reperfusion injury.
• Natural Product Development: Employed as a bioactive marker in the formulation and potency verification of herbal supplements and functional foods targeting circulatory support.
• Analytical Chemistry: Utilized as a high-purity standard for method development and validation in HPLC, LC-MS, and GC-MS analyses of complex botanical matrices.
• Preclinical Drug Discovery: Acts as a lead compound or intermediate for the synthesis of novel analogs with optimized pharmacokinetic properties for potential drug candidates.

Basic Information

Item	Detail
Product Name	Senkyunolide H
CAS No.	94596-27-7
Molecular Formula	C12H14O3
Molecular Weight	206.24 g/mol
Synonyms	Senkyunolide H; (3Z)-3-Butylidene-4,5-dihydro-7-hydroxy-6-methoxy-1(3H)-isobenzofuranone; (Z)-3-Butylidene-7-hydroxy-6-methoxyphthalide; 3-Butylidene-7-hydroxy-6-methoxyphthalide; Ligusticum lactone H; Phthalide derivative from *Ligusticum chuanxiong*
EINECS	Contact for details

Quality Control

Every batch of Senkyunolide H is produced and analyzed under strict quality management protocols. We provide comprehensive analytical documentation to support your research and regulatory needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.